Cailey Fleming Bea Ryan Reynolds Cal John Krasinski Dad / Marshmallow (voice) Fiona Shaw Grandmother Steve Carell Blue (voice) Phoebe Waller-Bridge Blossom (voice) Louis Gossett Jr. Lewis (voice) Alan Kim Benjamin Liza Colón-Zayas Janet Bobby Moynihan Jeremy Catharine Daddario Bea’s Mom Audrey Hoffman Bea (Ages 3 & 5) Laquet Sharnell Pringle Receptionist Ed Herbstman Deli Guy Barbara Andres Woman Upstairs Alexander Rivero Custodian Awkwafina Bubble (voice) Bradley Cooper Ice (voice) Matt Damon Flower (voice) Matthew Rhys Ghost (voice) Sam Rockwell Guardian Dog (voice)